Zebrafish retinal mutants
نویسندگان
چکیده
منابع مشابه
Zebrafish retinal mutants
We have initiated a genetic analysis of the zebrafish visual system to identify novel molecules involved in vertebrate retinal function. Zebrafish are highly visual; they have four types of cones as well as rod photoreceptors, making it possible to study both rod and cone-mediated visual responses. To identify visual mutants, optokinetic responses of mutagenized larvae are measured in a three-g...
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PURPOSE To characterize morphologic and physiological alterations in the retina of three laminin mutant zebrafish, bashful (bal, lama1), grumpy (gup, lamb1), and sleepy (sly, lamc1), which were identified in forward genetic screens and were found to be impaired in visual functions. METHODS Mutant larvae were observed for defects in visual behavior by testing their optokinetic response (OKR). ...
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ژورنال
عنوان ژورنال: Vision Research
سال: 1998
ISSN: 0042-6989
DOI: 10.1016/s0042-6989(97)00227-7